Research Associate, Vivarium (Job Code #VIVRA)

FLX Bio is a biotechnology company focused on the discovery and development of novel drugs that will improve and prolong the lives of people with cancer. The company is led by a group of seasoned researchers from the biotechnology and pharmaceutical industries and is supported by several of the nation’s premier life sciences venture capital firms. The company is located in the San Francisco Bay area, in the heart of the world’s largest biotechnology research hub. We offer a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants.

 

ESSENTIAL FUNCTIONS:

  • Works cross-functionally with multiple teams within the organization to achieve goals
  • Perform rodent dosing and blood collection to support pharmacokinetic (PK) studies
    • Proficient with intravenous, subcutaneous, intraperitoneal dosing as well as oral gavage
    • Experience with intratumoral dosing a plus
    • Knowledge of rat cannulation a plus
  • Conduct testing of anti-tumor agents in laboratory mice
    • Experienced with a variety of syngeneic and xenograft tumor models
    • Proficient with tumor cell injections; knowledge of orthotopic tumor models is a plus
    • Experienced with surgery procedures and harvest of various mouse tissues
  • Measure tumor size in laboratory mice
  • Monitor health of laboratory mice as specified by supervisors and staff veterinarians
  • Adhere to animal welfare rules and regulations as instructed by supervisors and vivarium managers
  • Light husbandry duties as required
  • Maintain and complete documentation of all study procedures and data in an electronic laboratory notebook
  • Willing to split weekend and holiday hours with peers on a rotational basis
  • Able to perform occasional physical labor involving lifting weight up to 50 pounds

 EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS:

  • Requires a Bachelor’s degree in Biology or related discipline with training in handling of rodents
    • AALAS certification highly desired (LAT, LATg)
  • 3-5 years of hands on experience with laboratory rodents and experience with pharmacokinetic studies and/or mouse tumor models is required
  • Proficiency in the following:
    • Dosing routes (IV, PO, SC)
    • Tumor implantation (SC, orthotopic)
    • Blood / Tissue collections (RO / various organs and lymph nodes)
  • Ability to multitask and meet deadlines in a fast-paced, dynamic environment
  • Organized and disciplined about record keeping, with proficiency in Microsoft Office
  • Able to perform occasional physical labor involving lifting weight up to 50 pounds
  • Excellent verbal and written communication skills
  • Strong organizational skills, motivated to excel, attentive to detail, and can be efficient working alone or in a group environment